St George Illawarra jumped over the Titans and out of last place with their first win of the season last round.
It came as the Gold Coast were comfortably beaten by the Rabbitohs, unable to repeat their success over the Wests Tigers a week earlier.
The Dragons are aiming for five consecutive wins against the Titans to build on the momentum they gained in beating the Sharks.
St George Illawarra beat Gold Coast twice in as many meetings in 2019.
Titans: New signing Corey Thompson starts at fullback, with Phillip Sami moving to the wing, Brian Kelly to centre and Dale Copley (ankle) out injured. Jaimin Jolliffe starts with Sam Lisone to come off the interchange. Beau Fermor and Jarrod Wallace dropped off the extended bench on game day after Jai Whitbread and Tyrone Roberts were cut from their squad 24 hours prior to kick-off. The Titans have won four of their past six games at Suncorp Stadium.
Dragons: Trent Merrin starts with James Graham moving to the bench. The Dragons omitted Korbin Sims and Tristan Sailor from their squad on Friday and Jackson Ford and Jason Saab an hour before kick-off. They have won five of their past seven games in Queensland.
There's not much to compare Matt Dufty and Tyrone Peachey on face value given their vastly different roles. But they share at least one trait in common: the ability to bust a game open. It might take just one magic moment to decide the result, and you sense these two X-factor players could be the ones to provide it.